by Leonard R. Johnson

Gain a foundational understanding of gastrointestinal physiology and how the GI system functions in health and disease. Gastrointestinal Physiology, a volume in the Mosby Physiology Series, explains the fundamentals of this complex subject in a clear and concise manner, while helping you bridge the gap between normal function and disease with pathophysiology content throughout the book.

Contents

• Chapter 1 Regulation: Peptides of the Gastrointestinal Tract
•        Objectives
•        General Characteristics
•        Discovery
•        Chemistry
•        Distribution and Release
•        Actions and Interactions
•        Candidate Hormones
•        Neurocrines
•        Paracrines
•        Clinical Applications
•        Clinical Tests
•        Summary
•        Key Words and Concepts
• Chapter 2 Regulation: Nerves and Smooth Muscle
•        Objectives
•        Anatomy of the Autonomic Nervous System
•        Neurohumoral Regulation of Gastrointestinal Function
•        Anatomy of the Smooth Muscle Cell
•        Smooth Muscle Contraction
•        Summary
•        Key Words and Concepts
• Chapter 3 Swallowing
•        Objectives
•        Chewing
•        Pharyngeal Phase
•        Esophageal Peristalsis
•        Receptive Relaxation of the Stomach
•        Clinical Applications
•        Clinical Tests
•        Summary
•        Key Words and Concepts
• Chapter 4 Gastric Emptying
•        Objectives
•        Anatomic Considerations
•        Contractions of the Orad Region of the Stomach
•        Contractions of the Caudad Region of the Stomach
•        Contractions of the GastroduodenalJunction
•        Contractions of the Proximal Duodenum
•        Regulation of Gastric Emptying
•        Clinical Applications
•        Clinical Tests
•        Summary
•        Key Words and Concepts
• Chapter 5 Motility of the Small Intestine
•        Objectives
•        Anatomic Considerations
•        Types of Contractions
•        Patterns of Contractions
•        Vomiting
•        Clinical Applications
•        Clinical Tests
•        Summary
•        Key Words and Concepts
• Chapter 6 Motility of the Large Intestine
•        Objectives
•        Anatomic Considerations
•        Contractions of the Cecum and Ascending Colon
•        Contractions of the Descending and Sigmoid Colon
•        Motility of the Rectum and Anal Canal
•        Control of Motility
•        Clinical Significance
•        Clinical Tests
•        Summary
•        Key Words and Concepts
• Chapter 7 Salivary Secretion
•        Objectives
•        Functions of Saliva
•        Anatomy and Innervation of the Salivary Glands
•        Composition of Saliva
•        Regulation of Salivary Secretion
•        Clinical Correlation
•        Summary
•        Key Words and Concepts
• Chapter 8 Gastric Secretion
•        Objectives
•        Functional Anatomy
•        Secretion of Acid
•        Origin of the Electrical Potential Difference
•        Electrolytes of Gastric Juice
•        Stimulants of Acid Secretion
•        Stimulation of Acid Secretion
•        Inhibition of Acid Secretion
•        Pepsin
•        Mucus
•        Intrinsic Factor
•        Growth of the Mucosa
•        Clinical Applications
•        Summary
•        Key Words and Concepts
• Chapter 9 Pancreatic Secretion
•        Objectives
•        Functional Anatomy
•        Mechanisms of Fluid and Electrolyte Secretion
•        Mechanisms of Enzyme Secretion
•        Regulation of Secretion
•        Cellular Basis for Potentiation
•        Response to a Meal
•        Clinical Applications
•        Summary
•        Key Words and Concepts
• Chapter 10 Bile Secretion and Gallbladder Function
•        Objectives
•        Overview of the Biliary System
•        Constituents of Bile
•        Bile Secretion
•        Gallbladder Function
•        Expulsion of Bile
•        Clinical Applications
•        Clinical Tests
•        Summary
•        Key Words and Concepts
• Chapter 11 Digestion and Absorption OF NUTRIENTS
•        Objectives
•        Structural-Functional Associations
•        Digestion
•        Absorption
•        Adaptation of Digestive and Absorptive Processes
•        Carbohydrate Assimilation
•        Protein Assimilation
•        Lipid Assimilation
•        Vitamins
•        Summary
•        Key Words and Concepts
• Chapter 12 Fluid and Electrolyte Absorption
•        Objectives
•        Bidirectional Fluid FluX
•        Ionic Content of Luminal Fluid
•        Transport Routes and Processes
•        Mechanism for Water Absorption and Secretion
•        Intestinal Secretion
•        Clinical Applications
•        Calcium Absorption
•        Iron Absorption
•        Summary
•        Key Words and Concepts
• Chapter 13 Regulation of Food Intake
•        Objectives
•        Appetite Control
•        The Nervous System
•        The Endocrine System
•        The Gastrointestinal System
•        Clinical Applications
• Summary
• Key Words and Concepts
• Appendix A Answer to Self-Study Problems
• Appendix B Comprehensive Multiple-Choice Review Examination
• Index